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    Tianeptine

    Categories

    habit-forming depressant opioid

    Tianeptine structure

    Summary

    A Tricyclic antidepressant, that has quite unique pharmacological properties than others in its class. Such as the possible indirect action on NMDA/AMPA and a full agonist at the μ-opioid receptor. While abuse of this substance is uncommon, it has been shown in a few countries.

    ⚠️ Tianeptine is reported to have opioid-like effects at high doses, but this is offset by an increased risk of liver damage

    Dose Information

    Onset, Duration & After-effects

    • Onset: 15-45 minutes
    • Duration: 4-6 hours
    • After-effects: 1-8 hours