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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Rolicyclidine Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 29 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Tentative
    • classified Research-chemical

    Aliases: Pcpy

    Summary PsychonautWiki

    Rolicyclidine (also known as PCPy, or sometimes PHP) is a simple dissociative substance of the arylcyclohexylamine class. Compared to plain PCP, it is almost unknown, despite a strikingly easier synthesis, employing unwatched pyrrolidine instead of piperidine. It produces its effects by both blocking the NMDA receptor and modulating monoamine transporters.

    Dose Information source varies by band

    ROA Light Common Strong Heavy
    Oral 3-5mg 5-9mg 9-13mg 13mg+
    Insufflated 2-4mg 4-8mg 8-15mg 15mg+
    Smoked 2-4mg 4-8mg 8-12mg 12mg+
    Light Common Strong Heavy
    Sources· 3 of 3 ladders not fully identified

    Oral

    Dose ladder — Light–Strong: DrugsPRO · Heavy: not identified

    Insufflated

    Dose ladder — Light–Strong: DrugsPRO · Heavy: not identified

    Smoked

    Dose ladder — Light–Strong: DrugsPRO · Heavy: not identified

    Onset, Duration & After-effects TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 18-90 min 0.5-2 hrs 2-3 hrs 3-4 hrs 12-48 hrs 2-6 hrs
    Insufflated 6-30 min 30-90 min 2-3 hrs 1-2 hrs 4-48 hrs 2-6 hrs
    Smoked 0-18 min 18-42 min 2-3 hrs 1-2 hrs 4-48 hrs 2-6 hrs

    Effect Profile

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 6.0
    Strong 6/10

    Strong dissociative depth with strong motor impairment, mild mania, low insight

    Dissociative Depth ×3
    10
    depersonalization derealization physical disconnection cognitive disconnection visual disconnection spatial disorientation +2 more
    ⚠ Mania / Compulsion ×1
    4
    disinhibition stimulation
    Insight / Novel Thought ×2
    3
    conceptual thinking
    ⚠ Motor / Sensory Impairment ×1
    10
    motor control loss physical disconnection tactile suppression numbness spatial disorientation visual disconnection +1 more

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2–4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Cross-Tolerances

    Dissociatives

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations TripSit

    Cross-Check Rolicyclidine with another substance

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    Helpful Links

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes Rolicyclidine, but its built-in data can be thinner than ours. Importing this file adds a separate "Rolicyclidine (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "Rolicyclidine (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.