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    Pentedrone molecular structure

    Pentedrone Stats & Data

    PubChem
    MW191.27
    FormulaC12H17NO
    LogP2.5
    IUPAC2-(methylamino)-1-phenylpentan-1-one
    SMILESCCCC(C(=O)C1=CC=CC=C1)NC
    InChIKeyWLIWIUNEJRETFX-UHFFFAOYSA-N
    Chemical Class Substituted cathinone
    Psychoactive Class Stimulant

    Receptor Profile

    Receptor Actions

    Inhibitors
    Norepinephrine-dopamine reuptake inhibitor (NDRI)
    Other
    minimal serotonin activity

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational pentedrone use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because pentedrone has a very short history of human usage. Early anecdotal evidence from people who have tried pentedrone within the community suggests that there do not seem to be any negative health effects attributed to simply trying this substance at low to moderate doses by itself and using it in a sparing and controlled fashion (but nothing can be completely guaranteed). It is strongly recommended that one use harm reduction practices when using this substance.

    Effect Profile

    Curated + 2 Reports
    Stimulant 3.8

    Strong euphoria with strong anxiety/jitters, mild stimulation

    Stimulation / Energy×3
    4
    Euphoria / Mood Lift×2
    9
    Focus / Productivity×2
    0
    Anxiety / Jitters×1
    10
    Based on reports from:

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 7d Baseline ~14d

    Experience Report Analysis

    Erowid
    6 Reports
    2 Single-substance
    2013–2025 Date Range
    6 With Age Data

    Demographics

    Gender Distribution

    Too few reports for a chart: gender is known from 6 reports, and a split is drawn only from 20 reports or more. Counts are shown instead. Why 20?

    • Male 5 of 6
    • Female 1 of 6

    Age Distribution

    Reports Over Time

    Real-World Dose Distribution

    Erowid

    From 10 of 11 recorded dose entries: those that state a weight (mg, g or µg), in routes with at least five of them. Values above Q3 + 3×IQR, far above what people typically take, are left out; they can include real heavy doses and overdoses, not only mistakes.

    Insufflated (n=9)

    Median: 10.0mg 25th: 8.0mg 75th: 10.0mg 90th: 10.0mg

    Form / Preparation

    Most common forms and preparations, as a share of the 5 reports that give one

    Too few reports for bars: these forms come from 5 reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    • Powder / Crystals 5 of 5

    Legal Status

    Country Status Notes
    Brazil Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.
    China As of October 2015 Pentedrone is a controlled substance
    Czech Republic Pentedrone is banned in the Czech Republic.
    Germany Pentedrone is an Anlage II controlled drug
    Switzerland Pentedrone is a controlled substance specifically named under Verzeichnis D.
    United Kingdom Pentedrone is a Class B drug in the United Kingdom as a result of the cathinone catch-all clause.
    United States On January 28, 2014, the DEA listed it, along with 9 other synthetic cathinones, on the Schedule 1 with a temporary ban, effective February 27, 2014.
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