Nalorphine
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- no dose data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- no dose data
Summary
Nalorphine is a mixed opioid agonist–antagonist. It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Nalorphine's nerd page
Pharmacology, chemical data, effect profiles, and more
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