Misoprostol
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- no dose data
- PubChem toxicity data
- 2 corroborating sources
- no dose data
- PubChem toxicity data
Summary
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the strength and frequency of contractions and decrease cervical tone.
Dose Warnings
“A self-administered overdose of 12 mg for a medical abortion resulted in upper gastrointestinal bleeding, hemodynamic instability, and multiorgan failure.” — toxicity literature
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