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    Metaclazepam molecular structure

    Metaclazepam Stats & Data

    NPS DataHub
    MW393.71
    FormulaC18H18BrClN2O
    CAS84031-17-4
    IUPAC7-bromo-5-(2-chlorophenyl)-2-(methoxymethyl)-1-methyl-2,3-dihydro-1,4-benzodiazepine
    SMILESCOCC1CN=C(c2ccccc2Cl)c2cc(Br)ccc2N1C
    InChIKeyWABYCCJHARSRBH-UHFFFAOYSA-N
    Chemical Class 1,4-Benzodiazepine
    Psychoactive Class Depressant

    Effect Profile

    Curated
    Benzodiazepine 4.7

    Strong euphoria with low anxiolysis, sedation, and cognitive impairment

    Anxiolysis×3
    3
    Sedation / Relaxation×2
    3
    Motor / Cognitive Impairment×1
    2
    Euphoria / Mood Lift×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

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