Meclonazepam Stats & Data
O=N(=O)c1ccc2NC(=O)C(C)N=C(c3ccccc3Cl)c2c1LMUVYJCAFWGNSY-VIFPVBQESA-NHistory & Culture
Meclonazepam was first synthesized by a research team at Hoffmann-La Roche during the 1970s as a benzodiazepine derivative structurally related to clonazepam. Early investigations identified potential anti-parasitic applications against Schistosoma mansoni, the parasitic flatworm responsible for schistosomiasis, though this therapeutic avenue was never developed to the point of clinical approval. The compound was never marketed as a pharmaceutical product. It later emerged on the grey market as a designer drug, though it has not achieved widespread popularity within recreational drug communities.
Effect Profile
CuratedStrong euphoria and anxiolysis with mild cognitive impairment, low sedation
Tolerance & Pharmacokinetics
drugs.wikiNo tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.
Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder
Experience Report Analysis
ErowidDemographics
Gender Distribution
Too few reports for a chart: gender is known from 1 report, and a split is drawn only from 20 reports or more. Counts are shown instead. Why 20?
- Male 1 of 1