JWH-200 Stats & Data
PubChem
MW384.5
FormulaC25H24N2O2
LogP4.2
IUPAC[1-(2-morpholin-4-ylethyl)indol-3-yl]-naphthalen-1-ylmethanone
InChIKey
SZWYXJHTNGJPKU-UHFFFAOYSA-N
Chemical Class
Naphthoylindole
Pharmacology
DrugBankMechanism of Action
/Synthetic cannabinoid/ agonistic activity on the CB1 receptor is responsible for elevating mood and inducing a feeling of well-being. Some /synthetic cannabinoid/ users have reported effects similar to or even stronger than those obtained by smoking cannabis, such as physical relaxation, changes in perception, and mild euphoria.
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
3d
Half tolerance
21d
Baseline
~28d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Experience Report Analysis
Erowid
4
Reports
2010–2013
Date Range
4
With Age Data
2
Effects Detected
Demographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 4 experience reports (4 Erowid)
4
Reports
2
Effects Detected
1
Positive
0
Adverse
1
Neutral
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 1
Euphoria
100.0%
70%
Adverse Effects 0
Real-World Dose Distribution
62K DosesFrom 10 individual dose entries
Smoked (n=9)
Median: 10.0mg
25th: 10.0mg
75th: 10.0mg
90th: 13.0mg
mg/kg median: 0.13
mg/kg 75th: 0.13
Form / Preparation
Most common forms and preparations reported