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    Hexen molecular structure

    Hexen Stats & Data

    Neh Ethyl-hexedrone N-ethylhexedrone hex-en n-ethyl-hexedrone
    NPS DataHub
    MW219.33
    FormulaC14H21NO
    IUPAC2-(ethylamino)-1-phenylhexan-1-one
    SMILESCCCCC(NCC)C(=O)c1ccccc1
    InChIKeyCWNKMHIETKEBCA-UHFFFAOYSA-N
    Phenethylamines Cathinones
    Chemical Class Substituted cathinone
    Psychoactive Class Stimulant

    Interaction Warnings

    ⚠ stimulants

    Ethyl-Hexedrone can be potentially dangerous in combination with other stimulants as it can increase one's heart rate and blood pressure to dangerous levels.

    ⚠ mdma

    The neurotoxic effects of MDMA may be increased when combined with amphetamine and other stimulants.

    ⚠ cocaine

    This combination may increase strain on the heart.

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational N-ethylhexedrone use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because N-ethylhexedrone has a very brief history of human usage. Early anecdotal reports from those who have tried N-ethylhexedrone suggests that there do not seem to be any negative health effects attributed to simply trying it at low to moderate doses by itself and using it in a sparing and controlled fashion (but nothing can be completely guaranteed). Some users have reported N-ethylhexedrone to be caustic to the nasal membrane when it is insufflated. A toxicology screening indicated that measured with yeast and SH-SY5Y cells, N-Ethylhexedrone seems to be the most toxic among the five cathionones tested.

    Effect Profile

    Curated + 7 Reports
    Stimulant 4.1

    Moderate stimulation and euphoria with strong anxiety/jitters

    Stimulation / Energy×3
    7
    Euphoria / Mood Lift×2
    6
    Focus / Productivity×2
    0
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 7d Baseline ~14d

    Experience Report Analysis

    Erowid
    13 Reports
    7 Single-substance
    2015–2024 Date Range
    13 With Age Data
    3 Effects Detected

    Demographics

    Gender Distribution

    Too few reports for a chart: gender is known from 13 reports, and a split is drawn only from 20 reports or more. Counts are shown instead. Why 20?

    • Male 9 of 13
    • Female 2 of 13
    • Not Specified 2 of 13

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 7 experience reports (7 single-substance Erowid)

    7 Reports
    3 Effects Detected
    2 Positive
    1 Adverse
    0 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Each bar is the share of reports mentioning the effect; its whisker, and the band on the rows below, is the 95% interval: where the share could plausibly be with other reports of the same kind.

    Too few reports for bars: these effects come from 7 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 2

    Stimulation 4 of 7 70%
    Music Enhancement 3 of 7 70%

    Adverse Effects 1

    Jaw Clenching 3 of 7 70%

    Also reported in combinations. In the 6 Hexen reports where another drug was taken too, 1 mentions hospital, emergency services or an overdose, 1 a seizure and 2 psychosis (too few reports for percentages). In the 7 single-substance reports: 1, 1 and 0. These are not in the figures above: they cannot be put down to Hexen alone, and a mention is not always something that happened to the writer.

    Real-World Dose Distribution

    Erowid

    From 11 of 14 recorded dose entries: those that state a weight (mg, g or µg), in routes with at least five of them. Values above Q3 + 3×IQR, far above what people typically take, are left out; they can include real heavy doses and overdoses, not only mistakes.

    Insufflated (n=11)

    Median: 20.0mg 25th: 10.0mg 75th: 22.5mg 90th: 37.0mg

    Form / Preparation

    Most common forms and preparations, as a share of the 11 reports that give one

    Too few reports for bars: these forms come from 11 reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    • Powder / Crystals 11 of 11

    Redose Patterns

    Redosing behavior across 12 reports

    6 of 12 Redosed
    2.1 Avg Doses
    50m Median Interval

    Too few reports for a chart: redosing is known from 12 reports, and a split is drawn only from 20 reports or more. Counts are shown instead. Why 20?

    • Single dose 6 of 12
    • Redosed 6 of 12
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