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    Flutazolam molecular structure

    Flutazolam Stats & Data

    NPS DataHub
    MW376.81
    FormulaC19H18ClFN2O3
    CAS27060-91-9
    IUPAC10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
    SMILESOCCN1C(=O)CN2CCOC2(c2ccccc2F)c2cc(Cl)ccc12
    InChIKeyWMFSSTNVXWNLKI-UHFFFAOYSA-N
    Chemical Class Oxazolobenzodiazepine
    Psychoactive Class Depressant

    Effect Profile

    Curated
    Benzodiazepine 7.4

    Strong anxiolysis and euphoria with mild cognitive impairment, low sedation

    Anxiolysis×3
    10
    Sedation / Relaxation×2
    3
    Motor / Cognitive Impairment×1
    4
    Euphoria / Mood Lift×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

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