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    Fentanyl

    Aliases: fent

    Categories

    opioid habit-forming depressant

    Fentanyl structure

    Summary

    Fentanyl is a synthetic opiate analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-opioid receptors and is historically used to treat breakthrough pain. Fentanyl is approximately 100 times more potent than Morphine, and is commonly used as a patch. Sometimes used as an adulterant for heroin, which has led to many overdose deaths.

    ⚠️ WARNING: Risk of post-acute withdrawal effects, including depression, anxiety disorder, psychosis, suicidal ideation in extreme cases.
    ⚠️ Due to Fentanyl's high potency, it is incredibly difficult to measure safely, and so can easily lead to overdose.

    Dose Information

    Onset, Duration & After-effects

    • Onset:
      • Buccal: 15-30 minutes
      • Insufflated: 5-15 minutes
      • Transdermal: 90-180 minutes
    • Duration:
      • Buccal: 1-4 hours
      • Insufflated: 1-4 hours
      • Transdermal: 48-72 hours

    Effects