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    DiPT molecular structure

    DiPT Stats & Data

    Diisopropyltryptamine
    PubChem
    MW244.37
    FormulaC16H24N2
    LogP4.1
    IUPACN-[2-(1H-indol-3-yl)ethyl]-N-propan-2-ylpropan-2-amine
    InChIKeyZRVAAGAZUWXRIP-UHFFFAOYSA-N
    Chemical Class Substituted tryptamine
    Psychoactive Class Psychedelic

    Receptor Profile

    Receptor Actions

    Agonists
    5-HT2A receptor agonist (full)
    5-HT2B receptor agonist (full)
    5-HT2C receptor agonist (full)
    Inhibitors
    Serotonin reuptake inhibitor (weak)

    History & Culture

    1959–1997

    DiPT was first characterized in the scientific literature by R.B. Barlow and colleagues in 1959. Alexander Shulgin began investigating the compound's effects in humans during the mid-1970s, with his initial findings dating to 1974 and basic properties disclosed in 1976. Shulgin published more detailed characterizations of DiPT alongside 5-MeO-DiPT in a 1980 journal article, followed by additional publications throughout the 1980s. A comprehensive synthesis and collection of human use reports appeared in Shulgin's 1997 book TiHKAL (Tryptamines I Have Known And Loved), which brought the compound to wider attention within the psychedelic research community. DiPT was subsequently encountered as a novel designer drug in Europe by 2005 and has since circulated online as a research chemical.

    DiPT's unusual property of producing primarily auditory rather than visual effects has generated interest for potential neurological research applications. Shulgin speculated that the compound might serve as a valuable tool for studying the auditory system, potentially helping to locate the pitch-processing center of the brain if combined with imaging techniques such as positron emission tomography. A small study was conducted administering DiPT to two individuals with perfect pitch to investigate whether any systematic relationship existed between a note's actual pitch and the perceived pitch under the drug's influence. The results revealed no meaningful correlation, though they reinforced observations that the pitch decrease produced by DiPT is not linear and involves genuine harmonic distortion rather than a simple uniform pitch shift.

    Subjective Effects

    Sensory
    Auditory
    • Enhancements
    • Distortions
    • Hallucinations

    Forked from Subjective Effect Documentation work by Josie Kins, August 2016. Via dose.wiki (CC0).

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational DiPT do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because DiPT is a research chemical with very little history of human usage. Anecdotal reports from those who have tried DiPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption. It is strongly recommended that one use harm reduction practices when using this drug.

    Addiction & dependence

    DiPT is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating. Tolerance to the effects of DiPT is built almost immediately after ingestion.

    Effect Profile

    Curated + 70 Reports
    Psychedelic 6.5

    Strong visuals and auditory effects with strong body load, mild headspace

    Visual Intensity×3
    10102.4
    Headspace Depth×3
    45.01.6
    Auditory Effects×1
    10106.2
    Body Load / Somatic Effects×1
    107.13.5
    Catalog Erowid BlueLight

    Duration Timeline

    Bluelight
    Onset Comeup Peak Offset After Effects
    Oral
    19 minutes - 1.0 hours
    30 minutes - 1.0 hours
    2-4 hours
    2-4 hours
    24 hours
    Total: 3-5 hours
    Smoked
    6-12 minutes
    12-24 hours
    Total: 15-60 minutes hours

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    Not well-established in humans; functional effects typically span several hours.
    Addiction Potential
    Low; not considered habit-forming, with little evidence of compulsive use.

    Tolerance Decay

    Full tolerance 6h Half tolerance 7d Baseline ~14d

    Rapid tolerance typical of serotonergic psychedelics; spacing doses by 1–2 weeks minimizes attenuation. Model values are heuristic from community reports (anecdotal).

    Cross-Tolerances

    Psilocybin/Psilocin
    DMT/MET/MiPT/DPT
    Lysergamides (e.g., LSD/AL-LAD)

    Experience Report Analysis

    Erowid BlueLight
    76 Reports
    46 Single-substance
    1999–2025 Date Range
    17 With Age Data
    22 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid + Bluelight

    Effects aggregated from 70 experience reports (46 single-substance Erowid + 24 Bluelight)

    70 Reports
    87 Effects Detected
    36 Positive
    28 Adverse
    23 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Each bar is the share of reports mentioning the effect; its whisker, and the band on the rows below, is the 95% interval: where the share could plausibly be with other reports of the same kind.

    Positive Effects 36

    Music Enhancement 69.6% (95% interval 55 to 81 percent) 70%
    Visual Distortions 48.6% (95% interval 37 to 60 percent) 75%
    Body High 37.1% (95% interval 27 to 49 percent) 79%
    Music Distortion 25.0% (95% interval 12 to 45 percent) 90%
    Euphoria 21.4% (95% interval 13 to 32 percent) 87%
    Color Enhancement 20.0% (95% interval 12 to 31 percent) 79%
    Stimulation 18.5% (95% interval 11 to 29 percent) 73%
    Closed-Eye Visuals 17.2% (95% interval 10 to 28 percent) 84%
    Joy 16.7% (95% interval 7 to 36 percent) 79%
    Introspection 12.8% (95% interval 7 to 23 percent) 71%
    Visual Trails 12.5% (95% interval 4 to 31 percent) 72%
    Entity Imagery 12.5% (95% interval 4 to 31 percent) 85%
    Bliss 12.5% (95% interval 4 to 31 percent) 78%
    Libido Enhancement 12.5% (95% interval 4 to 31 percent) 73%
    Contentment 12.5% (95% interval 4 to 31 percent) 85%
    Tactile Enhancement 11.4% (95% interval 6 to 21 percent) 80%
    Open-Eye Visuals 8.7% (95% interval 3 to 20 percent) 70%
    Empathy 8.6% (95% interval 4 to 18 percent) 90%
    Awe 8.3% (95% interval 2 to 26 percent) 70%
    Ego Inflation 8.3% (95% interval 2 to 26 percent) 70%

    Adverse Effects 28

    Nausea 34.3% (95% interval 24 to 46 percent) 88%
    Confusion 18.5% (95% interval 11 to 29 percent) 78%
    Anxiety 17.1% (95% interval 10 to 28 percent) 80%
    Vomiting 16.7% (95% interval 7 to 36 percent) 91%
    Tinnitus 16.7% (95% interval 7 to 36 percent) 88%
    Depersonalization 16.7% (95% interval 7 to 36 percent) 76%
    Restlessness 12.5% (95% interval 4 to 31 percent) 78%
    Dizziness 12.5% (95% interval 4 to 31 percent) 92%
    Motor Suppression 12.5% (95% interval 4 to 31 percent) 85%
    Disrupted Sleep Architecture 12.5% (95% interval 4 to 31 percent) 75%
    Pupil Dilation 10.0% (95% interval 5 to 19 percent) 76%
    Headache 8.3% (95% interval 2 to 26 percent) 78%
    Body Load 8.3% (95% interval 2 to 26 percent) 80%
    Insomnia 8.3% (95% interval 2 to 26 percent) 80%
    Double Vision 8.3% (95% interval 2 to 26 percent) 90%
    Blurred Vision 8.3% (95% interval 2 to 26 percent) 85%
    Field Narrowing 8.3% (95% interval 2 to 26 percent) 80%
    Panic 8.3% (95% interval 2 to 26 percent) 85%
    Fear 8.3% (95% interval 2 to 26 percent) 85%
    Memory Suppression 8.3% (95% interval 2 to 26 percent) 90%
    Show 8 more adverse effects
    Body Temperature Change 8.3% (95% interval 2 to 26 percent) 75%
    Dry Mouth 8.3% (95% interval 2 to 26 percent) 70%
    Stomach Cramps 8.3% (95% interval 2 to 26 percent) 62%
    Sweating 7.1% (95% interval 3 to 16 percent) 80%
    Muscle Tension 6.5% (95% interval 2 to 18 percent) 70%
    Auditory Suppression 4.2% (95% interval 1 to 20 percent) 80%
    Directional Hearing Distortion 4.2% (95% interval 1 to 20 percent) 80%
    Irritability 4.2% (95% interval 1 to 20 percent) 80%
    Show 23 neutral or unclassified mentions
    Auditory Effects 80.0% (95% interval 69 to 88 percent)
    Pitch Shifting 66.7% (95% interval 47 to 82 percent)
    Surface Breathing 29.2% (95% interval 15 to 49 percent)
    Pressure 20.8% (95% interval 9 to 40 percent)
    Time Dilation 12.5% (95% interval 4 to 31 percent)
    Thought Deceleration 12.5% (95% interval 4 to 31 percent)
    Ego Dissolution 10.0% (95% interval 5 to 19 percent)
    Focus Suppression 8.3% (95% interval 2 to 26 percent)
    Tingling 8.3% (95% interval 2 to 26 percent)
    Sedation 7.2% (95% interval 3 to 16 percent)
    Time Distortion 6.5% (95% interval 2 to 18 percent)
    Dissociation 6.5% (95% interval 2 to 18 percent)
    Peripheral Imagery 4.2% (95% interval 1 to 20 percent)
    Thought Acceleration 4.2% (95% interval 1 to 20 percent)
    Numbness 4.2% (95% interval 1 to 20 percent)
    Thought Disorganization 4.2% (95% interval 1 to 20 percent)
    Visual Drifting 4.2% (95% interval 1 to 20 percent)
    Thought Loops 4.2% (95% interval 1 to 20 percent)
    Internal Auditory Hallucination 4.2% (95% interval 1 to 20 percent)
    Frequent Urination 4.2% (95% interval 1 to 20 percent)
    Spatial Distortion 4.2% (95% interval 1 to 20 percent)
    Distractibility 4.2% (95% interval 1 to 20 percent)
    Volume Distortion 4.2% (95% interval 1 to 20 percent)

    Also reported in combinations. In the 30 DiPT reports where another drug was taken too, 5 (16.7%) mention hospital, emergency services or an overdose, 1 (3.3%) a seizure and 0 (0.0%) psychosis. In the 46 single-substance reports: 2.2%, 2.2% and 0.0%. These are not in the figures above: they cannot be put down to DiPT alone, and a mention is not always something that happened to the writer.

    Dosage Distribution

    Dose distribution from experience reports, one dose per report (the first listed). Doses above Q3 + 3×IQR, far above what people typically take, are left out of the median and range and listed under each route: most are real heavy doses or overdoses, not mistakes.

    Median: 50.0 mg IQR: 30.5–74.8 mg n=30

    1 report gave a dose above the typical range (250 mg), so it is not in the figures above. Listing a dose here does not mean it is safe.

    Show the report
    • 250 mg · another drug taken too

    Real-World Dose Distribution

    Erowid

    From 74 of 77 recorded dose entries: those that state a weight (mg, g or µg), in routes with at least five of them. Values above Q3 + 3×IQR, far above what people typically take, are left out; they can include real heavy doses and overdoses, not only mistakes.

    Oral (n=56)

    Median: 47.5mg 25th: 25.0mg 75th: 70.0mg 90th: 100.0mg

    Insufflated (n=11)

    Median: 15.0mg 25th: 5.0mg 75th: 100.0mg 90th: 100.0mg

    Smoked (n=6)

    Median: 14.75mg 25th: 10.5mg 75th: 19.38mg 90th: 22.5mg

    Common Combinations

    Most co-occurring substances, as a share of all 76 reports filed under DiPT; whiskers are 95% intervals

    Form / Preparation

    Most common forms and preparations, as a share of the 50 reports that give one; whiskers are 95% intervals

    Body-Weight Dosing

    Dose per kg of body weight, one dose per report (the first listed), from reports giving a weight of 30–250 kg. Doses above Q3 + 3×IQR, far above what people typically take, are left out of the median and range and listed under each route.

    Median: 0.552 mg/kg IQR: 0.408–0.987 mg/kg n=28

    1 report gave a dose above the typical range (3.243 mg/kg), so it is not in the figures above. Listing a dose here does not mean it is safe.

    Show the report

    Redose Patterns

    Redosing behavior across 52 reports

    7.7% (95% interval 3 to 18 percent) Redosed
    1.1 Avg Doses
    45m Median Interval

    Legal Status

    Country Status Notes
    Germany NpSG (Controlled) Controlled under the Neue-psychoaktive-Stoffe-Gesetz (New Psychoactive Substances Act) as of July 18, 2019. Production, import with intent to distribute, administration to others, and trading are punishable offenses. Possession is prohibited but not subject to criminal penalties.
    Japan Designated Substance Controlled as a Designated Substance (Shitei-Yakubutsu) under the Pharmaceutical Affairs Law. Both possession and sale are prohibited.
    Latvia Schedule I Listed as a Schedule I controlled substance under national drug control legislation.
    New Zealand Class C Classified as a Class C controlled substance due to its structural relationship to DMT, which is covered under analogue provisions in New Zealand drug law.
    Sweden Proposed for scheduling Sweden's public health agency recommended classifying DiPT as a hazardous substance on May 15, 2019. Current legal status may have changed following this recommendation.
    Switzerland Uncontrolled Not listed under Buchstabe A, B, C, or D of controlled substances legislation. May be considered legal to possess, though sale for human consumption could still raise regulatory issues.
    United Kingdom Class A Controlled as a Class A substance under the Misuse of Drugs Act 1971 due to the tryptamine catch-all clause, which covers structurally related compounds.
    United States Unscheduled (Federal Analogue Act may apply) Federally unscheduled, though it may be considered an analogue of DET or 5-MeO-DiPT under the Controlled Substances Act. Sales for human consumption or possession with intent to ingest could potentially be prosecuted under the Federal Analogue Act. Specifically listed as Schedule I in Florida and Louisiana (since June 2013).

    Harm Reduction

    drugs.wiki

    DiPT is notable for its unique auditory distortions—often downward pitch-shifting and nonlinear harmonic distortion—while visual changes are usually mild compared with other psychedelics. The altered pitch/timbre can persist into the next day in some users; to protect hearing and reduce disorientation, avoid loud venues, high headphone volumes, and tasks requiring accurate sound localization or timing (e.g., driving). Onset can be subtle; avoid redosing during the first 2–3 hours as tolerance rises quickly and effects may surge later. People with seizure disorders, on lithium, or taking serotonergic drugs (SSRIs/SNRIs/TCAs, tramadol, DXM, 5-HTP) should avoid DiPT due to seizure or serotonin-toxicity concerns. Set/setting and a sober sitter are recommended—auditory scene distortions can impair communication and situational awareness. Use drug checking: reagent tests help confirm a tryptamine (e.g., Ehrlich), but laboratory confirmation via GC/MS (e.g., DrugsData) best verifies identity. Data on non‑oral ROAs are sparse; oral is the best-characterized and most predictable route.

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