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    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Diclazepam Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 4 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 27 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: Chlorodiazepam, 2'-chloro-diazepam

    Summary dose.wiki TripSit PsychonautWiki

    Diclazepam is an unscheduled research chemical benzodiazepine not approved for medical use in most countries. It is structurally related to diazepam but approximately 10 times more potent in animal studies. Its long half-life of approximately 42 hours and active metabolites (delorazepam, lorazepam, lormetazepam) lead to accumulation with repeated use and prolonged effects lasting days.

    Dose Information dose.wiki Drugs.Wiki

    ROA Light Common Strong Heavy
    Oral 0.5-1mg 1-2mg 2-4mg 4mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, Drugs.Wiki

    Benzo Equivalence Calculator

    mg
    1.0 mg Diclazepam
    =
    β€” mg Diazepam

    ⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 10-90 min 1-3 hrs 2-6 hrs 4-12 hrs 48 hrs 8-12 hrs

    Effect Profile

    8 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 7.0
    Strong+ 7/10

    Strong anxiolysis with moderate cognitive impairment and euphoria, mild sedation

    Anxiolysis ×3
    10
    anxiety suppression anxiolytic muscle relaxation muscle relaxant emotion suppression
    Sedation / Relaxation ×2
    5
    sedation muscle relaxation
    ⚠ Motor / Cognitive Impairment ×1
    7
    motor control loss amnesia delusions of sobriety
    Euphoria / Mood Lift ×1
    6
    physical euphoria disinhibition

    Tolerance

    Build-up develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines Β· Alcohol and Drug Foundation: GHB Β· FDA 2020: benzodiazepine boxed warning Β· FDA 2019: gabapentinoids and breathing Β· NHS: alcohol use disorder

    Cross-Tolerances

    Other benzodiazepines
    Z-drugs (zolpidem, zopiclone)

    Effects dose.wiki TripSit

    Positive
    Negative
    Neutral
    Positive
    Negative
    Negative
    Neutral

    Combinations

    Cross-Check Diclazepam with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 2 positive 2 neutral 4 cautionary visit
    Is Not Alternative Diazepam cautionary exp #108407

    I am a man in my late 30s who has lived many lives. You can scroll to the line if you wish only to read the experience. In my past I have, at some point or other, ingested over 50% of all substances listed on Erowid, plus some that are not.

    Dicklazerspam · 2 mg sublingual / 60 mg oral / 1 g oral / 60 g oral
    Utilitarian Benzo positive exp #109776

    With the explosion of 'research chemical' benzos and benzo derivatives/analogues, I've had the opportunity to try a few (namely: etizolam, clonazolam, nifoxipam, and diclazepam) on many occasions.

    BenzoEater
    Take a Few Then Hide the Rest cautionary exp #103296

    I took a range of other drugs while under the influence of this drug. I remember taking: 7 gram of base (form of amphetamine in my country) Lots of weed Unsure how much alcohol, about a quarter of a litre of vodka 30mg of Amitriptyline Possibly more, memory was affected I order 50 of these small tablets (1mg each) from...

    guinnypig · 20 mg oral / repeated smoked / 250 ml oral / oral
    Steady Hands neutral exp #110440

    Steady Hands in the Land of Diclazepam Brief background on my use without sounding snoody: done most recreational pharms particularly stimulants benzos and opiates, am currently prescribed suboxone and have tried and tripped on most common substances and several uncommon ones.

    Mouse
    Subtle Long-Lasting Benzo neutral exp #109740

    I have had the experience of wanting a particular substance for an event or experience - MDMA for Bonnaroo, maybe, or a joint after a long hike - only to find that somebody forgot to pack a lighter, didn't bring the shrooms, or whatever - and the drugs never made it to their intended destination.

    BenzoTry
    Shorter but Otherwise Exactly Like Diazepam cautionary exp #109450

    Quick background: Not on any meds, mentally in a good place, exercise semi-regularly, have a pretty terrible diet. Plenty of drug experience, both Β“traditionalΒ” drugs and many RCs. IΒ’ve read countless reports of diclazepam being Β“utter shitΒ” and Β“almost entirely benignΒ”.

    Zirtonic · oral
    Ideal for Opiate Withdrawal cautionary exp #108007

    Diclazepam 2mg tablets were purchased from a RC vendor, Β£7.50 for x10 2mg tables. They're very small, almost identical in size to 2mg Roche Diazepam. The colour is a blue/mauve mix. Not unlike those old pimento candies. I originally asked my GP for help with coming off codeine.

    Tetrisdroid · 4 mg oral
    Similar to Lorazepam positive exp #110202

    Diclazepam. I got 120mg of it because I've been using etizolam to combat General anxiety disorder probably brought on by years of last drinking. I don't drink anymore. Etizolam seemed a miracle cure, and is still my favorite RC benzo for effects. It has alot good to be said about it.

    Jonnyboy369
    →

    Helpful Links

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes Diclazepam, but its built-in data can be thinner than ours. Importing this file adds a separate "Diclazepam (Substance Search)" custom substance with our dose ranges and durations, so you can log against whichever you prefer. It leaves tolerance out on purpose, for the reason given under Tolerance above.

    ⬇ Download import file Import this file as custom substances and you get "Diclazepam (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.