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    Cloniprazepam molecular structure

    Cloniprazepam Stats & Data

    NPS DataHub
    MW369.81
    FormulaC19H16ClN3O3
    IUPAC5-(2-chlorophenyl)-1-(cyclopropylmethyl)-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one
    SMILESO=N(=O)c1ccc2N(CC3CC3)C(=O)CN=C(c3ccccc3Cl)c2c1
    InChIKeyCCSYKGYLSFXNTA-UHFFFAOYSA-N
    Benzodiazepines
    Chemical Class 1,4-Benzodiazepine
    Psychoactive Class Depressant

    Effect Profile

    Curated
    Benzodiazepine 4.7

    Strong euphoria with low anxiolysis, sedation, and cognitive impairment

    Anxiolysis×3
    3
    Sedation / Relaxation×2
    3
    Motor / Cognitive Impairment×1
    2
    Euphoria / Mood Lift×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

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