I have been a long term user of opiates and am currently on 70mg of methadone daily. Since I started this stage of treatment at 90mg I have been coming down 5mg every month but I'm in no rush to come off it.
Butyrfentanyl
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 29 combo interactions documented
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 29 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: B-f, bf
Summary
Potent short-acting opioid and fentanyl analogue. Often dispensed in a nasal spray. This is an highly potent drug - exercise extreme caution.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 400-800ug | 800-1500ug | 1.5-3mg | 3mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Oral | 15-30 min | 3-4 hrs |
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
Falls quickly once you stop, at a rate you can't judge. After any break, treat your tolerance as gone.
No tolerance chart. Our decay curves for opioids were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
Opioid tolerance drops fast when you stop, and even a few days off can be enough, so a dose that used to be normal can now stop your breathing. Overdose deaths rise sharply after prison, detox or leaving treatment, and tolerance also falls during a hospital stay. After any break, start with a much smaller amount, try a test dose first, don't use alone, and keep naloxone within reach. Alcohol, benzodiazepines, gabapentinoids and other sedatives make an opioid overdose much more likely.
Sources: FRANK: heroin · National Harm Reduction Coalition · WHO: opioid overdose · Merrall et al. 2010 · Binswanger et al. 2007 · Strang et al. 2003 · FDA 2019: gabapentinoids and breathing
Combinations
Cross-Check Butyrfentanyl with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 1 report 1 neutral visit
Bluelight 1 thread 1 positive visit
I have tried to keep this report as objective as possible, please think very carefully before obtaining/consuming this substance. It is very compulsive, especially when smoked. Tolerance rises quickly and will carry over to other opioids.
Butyrfentanyl's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Butyrfentanyl there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
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Import this file as custom substances
and you get "Butyrfentanyl (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Name
Butyrfentanyl
Unit
µg
Description
Butyrfentanyl Source: SubstanceSearch (substancesearch.com) Oral dose (µg): light 400-800ug · common 800-1500ug · strong 1.5-3mg · heavy 3mg+ Oral duration: onset 15-30m · peak 3-4h · after-effects 1-4h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 1150 µg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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