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    bk-2C-B molecular structure

    bk-2C-B Stats & Data

    bk-2cb bk-2-cb b-k-2cb b-k2cb b-k2-cb b-k2-c-b b-k-2-c-b bk2cb
    PubChem
    MW274.11
    FormulaC10H12BrNO3
    LogP1.3
    IUPAC2-amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanone
    SMILESCOC1=CC(=C(C=C1C(=O)CN)OC)Br
    InChIKeyHFYJGAIOBIDRPX-UHFFFAOYSA-N
    Chemical Class Substituted cathinone
    Psychoactive Class Psychedelic

    History & Culture

    bk-2C-B was first characterized in the scientific literature in 2004 by pharmacologist Richard Glennon and his research team, who synthesized and studied the compound as part of investigations into phenethylamine structure-activity relationships. The substance remained largely obscure until 2013, when it emerged on European designer drug markets as a novel psychoactive substance. Following its market appearance, bk-2C-B maintained a consistent presence without generating significant enthusiasm or notoriety within the research chemical community. Despite this relatively muted reception, the compound was sampled by a substantial number of users over subsequent years. It was typically distributed in both pressed pill and powder forms. Its availability persisted in the gray market until regulatory measures were implemented across several countries beginning in 2016.

    Subjective Effects

    Physical
    • Spontaneous tactile sensations
    • Stimulation
    • Nausea
    • Tactile enhancement
    • Bodily control enhancement
    • Pupil dilation
    • Wakefulness
    Cognitive
    • Emotion enhancement
    • Thought acceleration
    • Novelty enhancement
    • Time distortion
    • Analysis enhancement
    • Personal bias suppression
    • Conceptual thinking
    • Immersion enhancement
    • Memory suppression
    • Ego death
    • Thought loops
    • Delusions
    • Thought disorganization
    Sensory
    Auditory
    • Enhancements
    • Distortions
    • Hallucinations
    Visual · Distortions
    • Drifting: (melting, flowing, breathing and morphing)
    • Tracers
    • After images
    • Symmetrical texture repetition
    • Colour shifting
    • Scenery slicing
    Visual · Enhancements
    • Acuity enhancement
    • Colour enhancement
    • Pattern recognition enhancement
    Visual · Hallucinatory States
    • Transformations
    • Internal hallucinations: (autonomous entities; settings, sceneries, and landscapes; alterations in perspective and scenarios and plots)

    Forked from Subjective Effect Documentation work by Josie Kins, August 2016. Via dose.wiki (CC0).

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational βk-2C-B use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because Bk-2C-B is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried Bk-2C-B suggests that there are no negative health effects attributed to simply trying the substance by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance.

    Effect Profile

    Curated + 9 Reports
    Psychedelic 4.6

    Strong visuals with mild auditory effects and body load, low headspace

    Visual Intensity×3
    8
    Headspace Depth×3
    1
    Auditory Effects×1
    4
    Body Load / Somatic Effects×1
    4

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Experience Report Analysis

    Erowid
    31 Reports
    9 Single-substance
    2012–2018 Date Range
    30 With Age Data
    15 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 9 experience reports (9 single-substance Erowid)

    9 Reports
    15 Effects Detected
    9 Positive
    5 Adverse
    1 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Each bar is the share of reports mentioning the effect; its whisker, and the band on the rows below, is the 95% interval: where the share could plausibly be with other reports of the same kind.

    Too few reports for bars: these effects come from 9 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 9

    Visual Distortions 7 of 9 70%
    Stimulation 5 of 9 70%
    Closed-Eye Visuals 4 of 9 70%
    Color Enhancement 4 of 9 70%
    Empathy 4 of 9 70%
    Body High 4 of 9 70%
    Music Enhancement 4 of 9 70%
    Euphoria 4 of 9 70%
    Introspection 3 of 9 70%

    Adverse Effects 5

    Anxiety 6 of 9 70%
    Pupil Dilation 6 of 9 70%
    Nausea 5 of 9 70%
    Confusion 4 of 9 70%
    Sweating 3 of 9 70%
    Show 1 neutral or unclassified mention
    Sedation 6 of 9

    Also reported in combinations. In the 22 bk-2C-B reports where another drug was taken too, 4 (18.2%) mention hospital, emergency services or an overdose, 1 (4.5%) a seizure and 2 (9.1%) psychosis. In the 9 single-substance reports: 2, 1 and 0. These are not in the figures above: they cannot be put down to bk-2C-B alone, and a mention is not always something that happened to the writer.

    Dosage Distribution

    Dose distribution from experience reports, one dose per report (the first listed). Doses above Q3 + 3×IQR, far above what people typically take, are left out of the median and range and listed under each route: most are real heavy doses or overdoses, not mistakes.

    Median: 150.0 mg IQR: 100.0–200.0 mg n=23

    Real-World Dose Distribution

    Erowid

    From 53 of 60 recorded dose entries: those that state a weight (mg, g or µg), in routes with at least five of them. Values above Q3 + 3×IQR, far above what people typically take, are left out; they can include real heavy doses and overdoses, not only mistakes.

    Oral (n=51)

    Median: 100.0mg 25th: 57.5mg 75th: 150.0mg 90th: 250.0mg

    Common Combinations

    Most co-occurring substances, as a share of all 31 reports filed under bk-2C-B; whiskers are 95% intervals

    Form / Preparation

    Most common forms and preparations, as a share of the 24 reports that give one; whiskers are 95% intervals

    Body-Weight Dosing

    Dose per kg of body weight, one dose per report (the first listed), from reports giving a weight of 30–250 kg. Doses above Q3 + 3×IQR, far above what people typically take, are left out of the median and range and listed under each route.

    Median: 2.151 mg/kg IQR: 1.48–2.689 mg/kg n=22

    Redose Patterns

    Redosing behavior across 26 reports

    38.5% (95% interval 22 to 58 percent) Redosed
    1.7 Avg Doses
    120m Median Interval

    Legal Status

    Country Status Notes
    Canada Controlled substance Became a controlled substance in October 2016. Possession, production, and distribution are prohibited under Canadian drug scheduling.
    Germany Controlled substance Classified as an illegal controlled substance. Manufacturing, possession, and distribution are prohibited without authorization.
    Switzerland Controlled substance Listed as a controlled substance under Swiss narcotics legislation. Unauthorized possession and distribution are prohibited.
    United Kingdom Controlled (Psychoactive Substances Act 2016) Prohibited under the Psychoactive Substances Act 2016, which broadly bans the production, supply, and importation of psychoactive substances intended for human consumption. Personal possession is not criminalized under this act, but supply-related offenses carry penalties of up to 7 years imprisonment.
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