Beta test rollout. This site is in community QA — please send feature requests, bug reports and data corrections on the Feedback page or on GitHub.

Home
    Disclaimer
    ← Back to Benzylfentanyl
    Benzylfentanyl molecular structure

    Benzylfentanyl Stats & Data

    Depressant Opioid
    PubChem CID 252141
    NPS DataHub
    MW322.45
    FormulaC21H26N2O
    CAS1474-02-8
    IUPACN-phenyl-N-[1-(phenylmethyl)piperidin-4-yl]propanamide
    SMILESCCC(=O)N(c1ccccc1)C1CCN(CC1)Cc1ccccc1
    InChIKeyPOQDXIFVWVZVML-UHFFFAOYSA-N
    Opioids
    Chemical Class Anilidopiperidine
    Psychoactive Class Depressant

    Pharmacology

    DrugBank
    State Solid

    Description

    Benzylfentanyl (R-4129) is a fentanyl analog opioid that was on the list of Schedule I drugs in America in 1985 due to its structural similarity to fentanyl. In 2010 it was removed from the list after it was found to have minimal opioid activity. Benzylfentanyl has a Ki of 213nM at the mu opioid receptor, binding around 200x less strongly than fentanyl itself.

    Effect Profile

    Curated
    Opioid 5.1

    Strong euphoria with moderate itching/nausea, mild sedation

    Euphoria / Warmth×3
    9
    Analgesia×2
    0
    Sedation / Relaxation×1
    5
    Itching / Nausea×1
    6
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Benzylfentanyl

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~35d
    ← Back to Benzylfentanyl