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    Disclaimer
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-FMC Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 4 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 29 combo interactions documented
    • classified Research-chemical

    Aliases: Drone, 4f-mcat, Flephedrone, Fpephedrone, 4-fluoromethcathinone, 4fmc

    Summary dose.wiki Erowid TripSit

    Pentedrone is a Schedule I controlled substance in the United States and is illegal in many countries. The toxicity and long-term health effects have not been studied in scientific contexts, and exact toxic dosage is unknown. Use accurate milligram scales for dosing.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-150mg 150-200mg 200mg+
    Insufflated 25-40mg 50-100mg 100-150mg 150mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, TripSit

    Insufflated

    Dose ladder — TripSit

    Onset, Duration & After-effects dose.wiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 20-40 min 30-60 min 1-2 hrs 30-60 min 2-6 hrs 2.33-4.67 hrs
    Insufflated 5-10 min 15-30 min 30-90 min 30-60 min 2-6 hrs 1.33-3.17 hrs

    Effect Profile

    1 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 7.7
    Intense 8/10

    Strong euphoria and sensory enhancement with moderate empathy, mild stimulation

    Empathy / Social Openness ×3
    7
    empathy enhancement sociability enhancement increased sociability
    Euphoria / Mood Elevation ×2
    10
    physical euphoria euphoria cognitive euphoria mood lift
    Stimulation ×1
    5
    stimulation teeth grinding increased heart rate
    Sensory Enhancement ×1
    8
    tactile enhancement spontaneous tactile sensations increased libido
    Stimulant 4.9
    Moderate+ 5/10

    Strong euphoria with strong anxiety/jitters, mild focus, low stimulation

    Stimulation / Energy ×3
    3
    stimulation
    Euphoria / Mood Lift ×2
    10
    physical euphoria euphoria cognitive euphoria mood lift motivation enhancement
    Focus / Productivity ×2
    5
    focus enhancement motivation enhancement
    ⚠ Anxiety / Jitters ×1
    10
    anxiety paranoia teeth grinding increased heart rate bruxism vasoconstriction +1 more
    Based on reports from:

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 2d Half tolerance 7d Baseline ~28d

    Tolerance to entactogenic/stimulant effects appears to build rapidly across a single day and decays over 1โ€“6 weeks. Values are rough, inferred from user reports for shortโ€‘acting cathinones; data quality is anecdotal.

    Cross-Tolerances

    Other stimulants (amphetamines, cathinones)

    Effects dose.wiki TripSit

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    • Visual and auditory hallucinations

    Combinations

    Cross-Check 4-FMC with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 3 reports 1 positive 2 neutral visit
    A Mildly Interesting Stimulant neutral exp #86047

    T= 0 = 01.05 am Setting: relaxed, at home, secure environment. The time of day was not optimal, but the time was available. Setting: I am not worried about the effects of this relatively little known material as I have read a few accounts of it and had tried taking in combination with other stimulants before with no al...

    Palmer Eldridge · 4-Fluoromethcathinone · rectal / rectal / 20 mg oral / 10 mg oral
    Boring Lackluster Cathinone neutral exp #110098

    First off, I've experienced legitimate Mephedrone previously on two occasions and since then various Mephedrone replacements. I acquired the 4-FMC with the hope that it might mimic some of the effects of 4-MMC, I'd previously taken 4-FMC from a different source and found it quite speedy but lacking entactogenically.

    Idiom · 4-Fluoromethcathinone · 50 mg insufflated / 50 mg insufflated / 150 mg insufflated / 2.5 ml oral
    Too Many Side Effects positive exp #84061

    Methedrone is soon to be scheduled as a class A drug. A successor, Flephedrone, aka 4-FMC or simply 'Flephe' amongst users, was introduced here last week, though it has been available elsewhere internationally. As of yet uncertain if it will catch on. I've read some mixed reviews so far.

    A in Sweden · 4-Fluoromethcathinone · repeated
    →

    Helpful Links

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes 4-FMC, but its built-in data can be thinner than ours. Importing this file adds a separate "4-FMC (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "4-FMC (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.