4-Fluorophenibut Stats & Data

F-Phenibut, designated by the developmental code name CGP-11130, is a GABA analogue that was investigated as a potential pharmaceutical agent but was never marketed. The compound belongs to a family of phenyl-substituted GABA derivatives that includes baclofen, tolibut, and phenibut, all of which share structural similarities as beta-phenyl-GABA analogues. Despite its origins in pharmaceutical research, F-Phenibut has more recently emerged as a novel psychoactive substance available through online research chemical vendors. The compound remains poorly characterized in the scientific literature, with limited formal research conducted on its pharmacological and toxicological properties.

F-Phenibut likely has a low toxicity relative to dose. However, it is potentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids. The toxicity and long-term health effects of recreational F-Phenibut use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because F-Phenibut has very little history of human usage. Anecdotal evidence from people who have tried this substance within the community suggests that there do not seem to be any negative health effects attributed to simply trying this substance at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed).

Effects aggregated from 4 experience reports (4 single-substance Erowid)

Each bar is the share of reports mentioning the effect; its whisker, and the band on the rows below, is the 95% interval: where the share could plausibly be with other reports of the same kind.

Too few reports for bars: these effects come from 4 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

Also reported in combinations. In the 3 4-Fluorophenibut reports where another drug was taken too, 1 mentions hospital, emergency services or an overdose, 0 a seizure and 0 psychosis (too few reports for percentages). In the 4 single-substance reports: 0, 0 and 0. These are not in the figures above: they cannot be put down to 4-Fluorophenibut alone, and a mention is not always something that happened to the writer.

From 137 of 138 recorded dose entries: those that state a weight (mg, g or µg), in routes with at least five of them. Values above Q3 + 3×IQR, far above what people typically take, are left out; they can include real heavy doses and overdoses, not only mistakes.

Most common forms and preparations, as a share of the 4 reports that give one

Too few reports for bars: these forms come from 4 reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

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