Doing drugs for the past 7 years with proper tolerance 2+week breaks. Might call myself a journeyman by this moment. Ate a slight breakfest ~1000cal. Can't say how much of 3-CMC I took as I don't know the total initial amount I purchased. The pack didn't have the weight and I don't have scales.
3-CMC
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: Clophedrone, 3-chloromethcathinone, 3cmc
Summary
3-CMC is a meta-chlorinated cathinone with significant neurotoxic and cardiotoxic concerns. Animal studies demonstrate neurotoxicity in mice, and its structural similarity to known neurotoxins like 4-CMA raises serious safety concerns. The compound is chemically unstable and degrades to potentially more toxic metabolites.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 30-60mg | 60-100mg | 100-180mg | 180mg+ |
| Insufflated | 20-40mg | 40-80mg | 80-100mg | 100mg+ |
Light
Common
Strong
Heavy
Sources
Oral
Dose ladder — dose.wiki, Drugs.Wiki, TripSitOnset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-90 min | 30-60 min | 60-90 min | 1-2 hrs | 3-6 hrs |
| Insufflated | 10-30 min | 15-30 min | 30-60 min | 30-60 min | 1.42-3 hrs |
Effect Profile
2 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Empathogen
6.0
Strong
6/10
Moderate empathy and stimulation with mild euphoria and sensory enhancement
Empathy / Social Openness
×3
7
empathy enhancement
sociability enhancement
increased sociability
Euphoria / Mood Elevation
×2
5
euphoria
mood lift
Stimulation
×1
6
stimulation
wakefulness
teeth grinding
Sensory Enhancement
×1
5
tactile enhancement
increased libido
Stimulant
3.2
Light+
3/10
Mild stimulation and euphoria with strong anxiety/jitters
Stimulation / Energy
×3
5
stimulation
wakefulness
Euphoria / Mood Lift
×2
5
euphoria
mood lift
Focus / Productivity
×2
0
Anxiety / Jitters
×1
9
anxiety
teeth grinding
bruxism
sweating
Based on reports from:
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Tolerance Decay
Full tolerance
2d
Half tolerance
10d
Baseline
~35d
Patterns inferred from stimulant/cathinone use reports: notable acute tachyphylaxis within a session, residual tolerance persisting days to weeks; robust evidence is lacking.
Cross-Tolerances
other cathinones (e.g., 3‑MMC, 4‑CMC)
amphetamine‑type stimulants
Effects
Effect glossary — · full glossary
Positive
Negative
Positive
Negative
Positive
Negative
- Visual and auditory hallucinations
Combinations
Cross-Check 3-CMC with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 2 reports 1 neutral 1 cautionary visit
I have had a nice time in the beginning, very MDMA-ish, I did it nasal, small lines every 10 minutes, in one night I did around 0.7 to 0.9 Grams of the substance.
Bluelight 1 thread 1 positive visit
Experience Report: 3-CMC Crystals Chemical Name (according to vendor) is 1-(3-chlorophenyl)-2-(methylamino)propan-1-one It has been very difficult to find information on this chemical, but if I come across anything else in my research, I will definitely post it here.
3-CMC's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 3-CMC there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
⬇ Download import file
Import this file as custom substances
and you get "3-CMC (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Name
3-CMC
Unit
mg
Description
3-CMC Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 30-60 · common 60-100 · strong 100-180 · heavy 180+ Insufflated dose (mg): light 20-40 · common 40-80 · strong 80-100 · heavy 100+ Oral duration: onset 0.5-1.5h · come-up 0.5-1h · peak 1-1.5h · offset 1-2h · total 3-6h · after-effects 4-12h Insufflated duration: onset 10-30m · come-up 15-30m · peak 0.5-1h · offset 0.5-1h · total 1.42-3h · after-effects 3-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 80 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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