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    Disclaimer
    ☠ NBOMe compounds are active at sub-milligram doses and have been linked to numerous deaths. They are frequently mis-sold as LSD. Always test substances before use.
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    25I-NBOMe Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 6 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 29 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: 25i, N-bomb, Smiles, Wizard, Cimbi-5, 2-c-i-nbome, 25-i

    Summary dose.wiki Erowid TripSit PsychonautWiki

    A relatively new and popular research chemical with psychedelic properties. Users report an uncomfortable body load with very strong visuals, though with less of a mental aspect than most psychedelics. Commonly missold as LSD, since it is much cheaper to produce. The drug is reported to be unsafe by many, and has caused several deaths at 'regular' doses.

    Dose Information source varies by route

    ROA Light Common Strong Heavy
    Sublingual 200-500Β΅g 500-700Β΅g 700-1000Β΅g 1000Β΅g+
    Buccal 200-500Β΅g 500-700Β΅g 700-1000Β΅g 1000Β΅g+
    Insufflated 200-500Β΅g 500-700Β΅g 700Β΅g+ -
    Light Common Strong Heavy
    Sources

    Sublingual

    Dose ladder — Light: PsychonautWiki, TripSit · Common: dose.wiki, PsychonautWiki · Strong: dose.wiki, PsychonautWiki, TripSit · Heavy: dose.wiki, TripSit

    Buccal

    Dose ladder — Light: same as the Sublingual row (PsychonautWiki, TripSit) · Common: same as the Sublingual row (dose.wiki, PsychonautWiki) · Strong: same as the Sublingual row (dose.wiki, PsychonautWiki, TripSit) · Heavy: same as the Sublingual row (dose.wiki, TripSit); no source states these Buccal figures

    Insufflated

    Dose ladder — PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Sublingual 0.25-2 hrs 0.5-2 hrs 2-4 hrs 1-4 hrs 72-144 hrs 5-10 hrs
    Buccal 0.25-2 hrs 0.5-2 hrs 2-4 hrs 1-4 hrs 72-144 hrs 5-10 hrs
    Oral 15-45 min 45-90 min 3-5 hrs 2-3 hrs 6-24 hrs 5-10 hrs
    Insufflated 6-12 min 12-30 min 1-2 hrs 2-3 hrs 1-7 hrs 4-6 hrs

    Effect Profile

    184 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 122 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, and auditory effects with strong body load

    Visual Intensity ×3
    10
    internal hallucinations colour enhancement autonomous entities drifting tracers synaesthesia +9 more
    Headspace Depth ×3
    10
    conceptual thinking introspection thought connectivity recursion emotion enhancement perspective alterations +3 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations auditory hallucination synaesthesia
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea vasoconstriction temperature regulation suppression muscle tension increased heart rate

    Tolerance

    Build-up develops rapidly after a single use; redosing is especially dangerous
    Reset 7–14 days for baseline

    Tolerance Decay

    Half tolerance 7d Baseline ~14d

    Tolerance builds rapidly after a single dose and partially recovers over 3–7 days; near‑baseline typically returns after 1–2 weeks. Cross‑tolerance with other serotonergic psychedelics is expected. Values are heuristic (community/HR synthesis). Data quality: low/anecdotal.

    Cross-Tolerances

    LSD
    2C-x
    DOx
    Other NBOMe compounds

    Effects Erowid Bluelight

    Aggregated from 122 single-substance Erowid and 62 Bluelight experience reports (the Bluelight figures come from the 50 of them read for effects); 104 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Positive Effects 62

    61.6% (95% interval 54 to 69 percent) 82%
    54.1% (95% interval 47 to 61 percent) 85%
    39.0% (95% interval 32 to 46 percent) 85%
    38.3% (95% interval 31 to 46 percent) 84%
    30.8% (95% interval 24 to 38 percent) 79%
    26.8% (95% interval 21 to 34 percent) 89%
    26.1% (95% interval 20 to 33 percent) 80%
    Auditory Effects 25.6% (95% interval 20 to 33 percent) 82%
    22.7% (95% interval 17 to 30 percent) 78%
    19.2% (95% interval 14 to 26 percent) 84%
    19.2% (95% interval 14 to 26 percent) 87%
    18.0% (95% interval 10 to 31 percent) 84%
    18.0% (95% interval 10 to 31 percent) 84%
    16.0% (95% interval 8 to 28 percent) 87%
    16.0% (95% interval 8 to 28 percent) 85%
    14.0% (95% interval 7 to 26 percent) 80%
    12.2% (95% interval 8 to 18 percent) 82%
    12.0% (95% interval 6 to 24 percent) 82%
    10.0% (95% interval 4 to 21 percent) 85%
    10.0% (95% interval 4 to 21 percent) 83%
    Show 42 more positive effects
    9.0% (95% interval 5 to 15 percent) –
    8.0% (95% interval 3 to 19 percent) 84%
    8.0% (95% interval 3 to 19 percent) 79%
    8.0% (95% interval 3 to 19 percent) 79%
    6.0% (95% interval 2 to 16 percent) 72%
    6.0% (95% interval 2 to 16 percent) 87%
    6.0% (95% interval 2 to 16 percent) 83%
    6.0% (95% interval 2 to 16 percent) 82%
    6.0% (95% interval 2 to 16 percent) 87%
    4.9% (95% interval 2 to 10 percent) –
    4.1% (95% interval 2 to 9 percent) –
    4.0% (95% interval 1 to 14 percent) 92%
    4.0% (95% interval 1 to 14 percent) 85%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 82%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 85%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 92%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 75%
    4.0% (95% interval 1 to 14 percent) 82%
    4.0% (95% interval 1 to 14 percent) 85%
    4.0% (95% interval 1 to 14 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 70%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 80%

    Adverse Effects 56

    58.1% (95% interval 51 to 65 percent) 83%
    38.9% (95% interval 32 to 46 percent) 80%
    25.0% (95% interval 19 to 32 percent) 88%
    18.0% (95% interval 10 to 31 percent) 83%
    14.0% (95% interval 7 to 26 percent) 85%
    14.0% (95% interval 7 to 26 percent) 91%
    14.0% (95% interval 7 to 26 percent) 91%
    12.0% (95% interval 6 to 24 percent) 83%
    11.6% (95% interval 8 to 17 percent) 85%
    10.0% (95% interval 4 to 21 percent) 78%
    10.0% (95% interval 4 to 21 percent) 81%
    10.0% (95% interval 4 to 21 percent) 79%
    9.9% (95% interval 6 to 15 percent) 81%
    9.8% (95% interval 6 to 16 percent) –
    8.2% (95% interval 5 to 13 percent) 87%
    8.2% (95% interval 4 to 14 percent) –
    8.0% (95% interval 3 to 19 percent) 81%
    8.0% (95% interval 3 to 19 percent) 80%
    8.0% (95% interval 3 to 19 percent) 82%
    7.4% (95% interval 4 to 13 percent) –
    Show 36 more adverse effects
    7.0% (95% interval 4 to 12 percent) 78%
    7.0% (95% interval 4 to 12 percent) 77%
    6.4% (95% interval 4 to 11 percent) 80%
    6.0% (95% interval 2 to 16 percent) 75%
    6.0% (95% interval 2 to 16 percent) 62%
    4.0% (95% interval 1 to 14 percent) 72%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 82%
    4.0% (95% interval 1 to 14 percent) 82%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 85%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 90%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 85%
    4.0% (95% interval 1 to 14 percent) 85%
    2.0% (95% interval 0 to 10 percent) 70%
    2.0% (95% interval 0 to 10 percent) 70%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 90%

    Also reported in combinations. In the 104 25I-NBOMe reports where another drug was taken too, 19 (18.3%) mention hospital, emergency services or an overdose, 6 (5.8%) a seizure and 5 (4.8%) psychosis. In the 122 single-substance reports: 22.1%, 7.4% and 8.2%. These are not in the figures above: they cannot be put down to 25I-NBOMe alone, and a mention is not always something that happened to the writer.

    Combinations TripSit

    Cross-Check 25I-NBOMe with another substance

    Trip Reports Effect Index

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 3 positive 1 neutral 4 cautionary visit
    Breakthrough positive exp #105849

    [Erowid Note: The doses described in this report are potentially life threatening. The amount taken is beyond a heavy dose and could pose serious health risks or result in unwanted, extreme effects. Doses such as this have been known to cause hospitalizations and/or deaths.

    Java · 25i-NBOMe · buccal
    Dynamic Range, Psychic Awakening neutral exp #93870

    Set: I've been feeling really bound up psychologically, very self-constrained, and I thought a psychedelic experience would do me good - a little WD-40 for the soul. Setting: My flat during the autumn. Previous experience: a just-over-threshold dose of LSD many, many years ago (Yup, that's it - not even weed).

    m · 1.5 mg buccal
    Happy Fun Wreck-Time positive exp #100130

    IΒ’ve tripped on 25I before. Sure, it was sold as mescaline the first time and I didnΒ’t know better, but IΒ’ve done it before. Loved it. Was a small dose I think, didnΒ’t know then, guessing now that it was probably 500 Β– 700 Β΅g. My first trip was with my friend D.

    obscuredbyclouds · 1 hit sublingual
    You Took Too Much Man cautionary exp #101923

    This is a story of my psychedelic year 2012 and how it ended horrificly. I've been going through what exactly happened that day and processing the events that led to it. It has been my intention for a while to write an experience report about it, but it was not until today that I decided that I'm ready.

    psycho · 2500 ug insufflated
    Glitchy Ego Death cautionary exp #103831

    The day that would change my life forever began with a text from our school, stating that classes will be cancelled for the day due to inclimate weather. A fresh sheet of ice and snow covered nearly every road in town, promising a wreck to almost anyone who went out.

    smiles · 2 bowls smoked / 1 hit oral
    Multiple Perspective NBOMe Freakout cautionary exp #98945

    FROM THE TRIP SITTER: T-00:00 My friend R took the single tab and placed it under his tongue for 10 minutes, commenting on the bitter taste. T-00:03 R then goes on to explain the numbness on his tongue.

    TheUtopinator · 25I-NBOMe (Sold as LSD) · 1 hit sublingual
    Worst Trip Ever cautionary exp #100170

    [Erowid Note: A substance(s) in this report might be identified incorrectly. Erowid reviewers question the author's identification of the drug described. Although the report is included in the collection, the substance might be something other than the author believed it to be.] I am submitting this report in hopes tha...

    rainbowrider · 1 hit buccal
    Geometric Bliss positive exp #101866

    [Erowid Note: The doses described in this report are potentially life threatening. The amount taken is beyond a heavy dose and could pose serious health risks or result in unwanted, extreme effects. Doses such as this have been known to cause hospitalizations and/or deaths.

    Jamaican Hotbox · 1000 ug sublingual / smoked / 1 cig. smoked / 2000 ug sublingual
    Bluelight 7 threads 2 positive 2 neutral 3 cautionary visit
    25i Nbome 1200ug Blotter 3rd Time I Stopped Taking Drugs Because Of This neutral

    I feel that this trip report needs a short introduction, so bear with me guys. 25i-NBOMe is one of those drugs that I'm not sure about. On the one hand its one of the strongest psychedelics I've ever tried, but on the other I feel like there is an element missing to its high, something I can't put my thumb on, one of m...

    1200 Β΅g mentioned in the thread; auto-extracted, unverified
    25i Nbome Sublingually 3 75mg positive

    25i-NBOMe sublingually, 3.75mg - Inexperienced Hello there, I'm here to report on my experience a couple nights ago with this novel compound, 25i-NBOMe, or 2c-i-NBOME, I see it written so many different ways.

    3.75 mg sublingual mentioned in the thread; auto-extracted, unverified
    25i Nbome 1000ug Blotter Fairly Experienced How I Spent The Last Day On Earth neutral

    Here is a short story I wrote about an 18 year old lad, Experimenting with the research chemical, 25i-NBOMe. December 21st 2012. The β€˜Last day on earth’ My first ever trip report on my most visual trip to date. Herein is my second?* experience with 25i-NBOMe.

    1000 Β΅g mentioned in the thread; auto-extracted, unverified
    25i N Bome 1 Mg positive

    It has almost been a year since the time of year I took 25i for the first time. This memory is very vivid, i just wanted to finally tell someone about it. So March of 2014 I was a senior in highschool nearing the end of it.

    1 mg mentioned in the thread; auto-extracted, unverified
    25i Inexperienced The Dancing Outlaw cautionary

    I told bits and pieces of this story to my partner the other day. I showed him the goosebumps on my arms and my shirt drenched in sweat as I concluded parts of the story. It's more or less humorous and light harted. It takes place a number of years ago, springtime.

    Detailed 25i Hospital Trip Report cautionary

    Dosage: 6 gummies or 12 drops of liquid 25i Route: orally Duration: 6 hours Medical Conditions: none My friend George was a 15 year old male (but is now 18 so it’s okay) from Vermont. George had a lot of experience with weed and other drugs but had taken no psychedelics before this day.

    25i Nbome Four Drops First Time Bonnaroo 2015 Near Death Experience cautionary

    Let me first start off by thanking everyone who took time out of their day to read this post. I would also like to state that prior to taking 25I I have never had any experience with psychedelics and this would be my first post ever on blue light but I've been a frequent lurker.

    Dose.wiki 1 report 1 neutral visit
    Ego death and a total break through in the snow 3 tabs - unknown oral neutral

    My perception of time and the order of events is really off but I would say I started to feel effects in 10-20 minutes after taking it, it numbed my tongue and tasted of harsh chemicals, the first things I noticed were, a bright pink field in the air, almost…

    by Anonymous

    Bluelight Reference Guide Bluelight

    β˜› Official ☚ The Big & Dandy 25I-NBOMe Thread - 4th Instance

    Welcome to The Big & Dandy 25I-NBOMe Thread (fourth edition) (previous thread) // (thread before that) // (even previouser thread) Subthreads: Combinations Reagent drug test info for NBOMe compounds Trip Reports: 25I-NBOMe Trip Reports External Links: Wikipedia Page Erowid Vault Taken From Wikipedia 25I-NBOMe acts as a...

    Read full thread on Bluelight β†’
    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has 25I-NBOMe, but its built-in entry only covers Insufflated, Sublingual. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "25I-NBOMe (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Custom Unit doses
    • Buccalcommon ~ 600 Β΅g
    Dose & duration (reference)
    25I-NBOMe: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    Buccal dose (Β΅g): threshold 50-250 Β· light 200-500 Β· common 500-700 Β· strong 700-1000 Β· heavy 1000+
    
    Buccal duration: onset 0.25-2h Β· come-up 0.5-2h Β· peak 2-4h Β· offset 1-4h Β· total 5-10h Β· after-effects 72-144h
    Oral duration: onset 15-45m Β· come-up 0.75-1.5h Β· peak 3-5h Β· offset 2-3h Β· total 5-10h Β· after-effects 6-24h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.