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    25E-NBOMe molecular structure

    25E-NBOMe Stats & Data

    25e
    NPS DataHub
    MW329.44
    FormulaC20H27NO3
    CAS1354632-14-6
    IUPAC2-(4-ethyl-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine
    SMILESCOc1ccccc1CNCCc1cc(OC)c(CC)cc1OC
    InChIKeyPXDVGFGXPVCNAB-UHFFFAOYSA-N
    Phenethylamines
    Chemical Class N-benzylphenethylamine
    Psychoactive Class Psychedelic

    History & Culture

    25E-NBOMe first appeared in scientific literature around 2012, emerging as part of the broader NBOMe series of substituted phenethylamines. This class of compounds, which includes related substances such as 25I-NBOMe and 25C-NBOMe, gained attention during this period as novel psychoactive substances. Following its initial scientific documentation, 25E-NBOMe subsequently appeared on the recreational drug market alongside other members of this chemical family.

    Effect Profile

    Curated + 1 Reports
    Psychedelic 2.8

    Mild visuals with moderate body load, low headspace

    Visual Intensity×3
    4
    Headspace Depth×3
    2
    Auditory Effects×1
    0
    Body Load / Somatic Effects×1
    6
    Based on reports from:

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    LSD
    Psilocybin
    Psilocin
    Mescaline
    DMT
    5-MeO-DMT
    2C-B
    2C-E

    Experience Report Analysis

    Erowid
    3 Reports
    1 Single-substance
    2014–2022 Date Range
    3 With Age Data

    Demographics

    Gender Distribution

    Too few reports for a chart: gender is known from 3 reports, and a split is drawn only from 20 reports or more. Counts are shown instead. Why 20?

    • Male 3 of 3

    Age Distribution

    Reports Over Time

    Form / Preparation

    Most common forms and preparations, as a share of the 3 reports that give one

    Too few reports for bars: these forms come from 3 reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    • Liquid 2 of 3

    Legal Status

    Country Status Notes
    Sweden Narcotic substance Classified as a narcotic substance by Sweden's public health agency on January 18, 2019. This classification places it under the same regulatory framework as other controlled narcotics in Swedish law.
    United Kingdom Class A Controlled under the Misuse of Drugs Act 1971 through the N-benzylphenethylamine catch-all clause. Class A substances carry the most severe penalties, with possession punishable by up to 7 years imprisonment and supply offenses carrying maximum life sentences.
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